Table 1.
Mathematical modelling approach | Model system | Comparison with experimental data | Reference |
---|---|---|---|
PBE (age, multistaged) | CHO and mouse–mouse hybridoma cell lines | Total cell count temporal profile | Abu‐Absi and Srienc (20) |
Exponential growth with cell loss | Muscle‐derived stem cells | Total cell count temporal profile (fitting) | Deasy et al. (14) |
PBE (DNA content, multistaged) | Human cancer cell line | Distributions of DNA content (fitting) | Basse et al. (26) |
PBE (mass, structured, multistaged) | Hybridoma and animal cell lines | Total cell count, substrates, and products temporal profiles (fitting) | Sidoli et al. (24) |
PBE (mass) | Human cancer cell lines | Total cell count, tumour radius and mass temporal profiles (fitting) | Busini et al. (27) |
PBE (volume, structured, multistaged) | Myeloma cell line | Total cell count, substrates, products, and cell phase fractions temporal profiles (fitting) Distributions of DNA content (qualitative comparison) | Liu et al. (28) |
PBE (age, multistaged) | Human leukaemia cells | Cell phase fractions temporal profiles (fitting) | Sherer et al. (23) |
PBE (protein content, multistaged) | Yeast | Distributions of protein content (qualitative comparison) | Hatzis and Porro (29) Cipollina et al. (21) |
PBE, Population Balance Equation.