Table 2.
Tumour growth parameters according to the model
Parameters | Tumour group 1 | Tumour group 2 | Tumour group 3 | Literature data (range) (reference) |
---|---|---|---|---|
Length of S phase | 6.67 h | 11 h | 20 h | 11 h 26 |
13.7 h (7.3–37.5) 30 | ||||
Mean cell‐cycle time (range) | 20 h (12–36) | 33 h (20–60) | 60 h (36–108) | 33 h (20–60) 26, 31 |
Volume doubling time | 31 days | 52 days | 96 days | 45 days (33–150) 32 |
Labelling index | 4.71% | 4.69% | 4.67% | 8% (1.2–30) 30 |
Cell division rate (24 h) | 2.3% | 1.3% | 0.74% | — (derived from the model) |
Pre‐treatment percentage of cancer stem cells | 5.37% | 5.42% | 5.36% | Tang et al. 6 |
Harper et al. 7 | ||||
Cell loss factor | 85% | 85% 33 |