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Efficacy of TBI-166 in the acute mouse infection model. Dosages are in milligrams per kilogram of body weight. At the beginning of treatment at day 10 postinfection, there were 2.97 ± 0.17 log10 CFU in the lungs of untreated mice. Values were determined after 20 days of treatment in BALB/c mice infected with M. tuberculosis H37Rv.
