TABLE 2.

MICs for CFZ and TBI-166 against rv0678 mutant and wild-type M. tuberculosis strains

Strain	Sequence or mutation by gene			MIC (μg/ml) by drug
	rv0678	pepQ	atpE	Bedaquiline	CFZ	TBI-166
BDQ-1	C305T	WT	WT	0.49	1.34	0.18
BDQ-2	292–316 nt deletion	WT	WT	0.47	1.29	0.19
BDQ-3	C403T	WT	WT	0.47	1.62	0.19
H37Rv	WT	WT	WT	0.06	0.14	0.060