TABLE 1.

Inhibitory effect of ACV on parental and recombinant viruses, as determined in a plaque reduction assay in Vero and MRC-5 cells

Virus	IC50 (μg/ml) ina:
	Vero cells	MRC-5 cells
HSV-1 F	0.3 ± 0.5	0.1 ± 0.04
HSV-1_VZV-TK	2.1 ± 0.5	3.4 ± 1.4
HSV-1_HSV1-TK	0.3 ± 0.03	0.1 ± 0.03
VZV vOka	NDb	1.0 ± 0.5

^aValues include standard deviations from three independent tests.

^bND, not determined.