FIG 2.

Vancomycin trough concentrations versus creatinine levels (top row) and bodyweight (bottom row) after the standard dosing regimen (green and red) and optimized dosing regimen (blue). Results were stratified for age group (by column). The dashed black horizontal lines represent the target exposure (i.e., 400 h·mg/liter). Dots represent the mean median values from 2,000 simulations, and the error bars represent the mean 5th and 95th percentiles. The parentheses symbol on the x axes indicate equal to and larger than, and the bracket symbol indicates smaller than.