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PKPD analysis of efficacy
| Organism | Study size (n) | Died (n) | Recurrence (n) | Microbiological failure (n) | MIC [mg/liter; mean (range)] | AUC/MIC [mg/liter; mean (range)] |
|---|---|---|---|---|---|---|
| All | 102 | 3 | 6 | 7 | 2 (0.12–4) | 320 (50–2,755) |
| CoNS | 80 | 3 | 5 | 7 | 2 (0.5–4) | 260 (50–846) |
| Micrococcus luteus | 1 | 0 | 0 | 0 | 0.12 | 2755 |
| Unknown | 10 | 0 | 1 | 0 | 1 (0.5–2) | 348 (127–620) |
| S. aureus | 9 | 0 | 0 | 0 | 2 (0.5–2) | 369 (125–1,007) |
| Viridans streptococci | 2 | 0 | 0 | 0 | 1 (0.5–1) | 1155 (364–1,947) |
