TABLE 8.
Overview of refined pediatric initial dosing regimen
| Creatinine band (μmol/liter) | 0–1 mo |
1 mo to 2 yr |
2–12 yr |
>12 yr |
||||
|---|---|---|---|---|---|---|---|---|
| eGFR (ml/min) | Dosage, q8h (mg/kg) | eGFR (ml/min) | Dosage, q6h (mg/kg) | eGFR (ml/min) | Dosage, q6h (mg/kg) | eGFR (ml/min) | Dosage, q8h (mg/kg) | |
| (15–30] | 84.2 | 20 | 123 | 20 | 197 | 20 | 272 | 35 |
| (30–50] | 47.4 | 15 | 69.4 | 15 | 111 | 15 | 153 | 25 |
| (50–90] | 27.1 | 10 | 39.7 | 10 | 63.2 | 10 | 87.5 | 15 |
| >90 | 21.1 | 10a | 30.9 | 5 | 49.2 | 5 | 68.0 | 7.5 |
a
Not supported by data, as no patients were available in this category. eGFR, estimated glomerular filtration rate, (k × height)/plasma creatinine.