TABLE 1.
MICs of antibiotics of different structural families in the selected P. aeruginosa PA14 aminoglycoside-hypersusceptible mutants
| Mutant | MIC (μg/ml)a |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| TGC | TET | CIP | CAZ | IPM | ATM | FOF | ERY | CHL | |
| PA14 | 8.0 | 2.0 | 0.125 | 1.0 | 0.75 | 2.0 | 8.0 | 96.0 | 24.0 |
| PA3016 | 6.0 | 1.5 | 0.094 | 1.5 | 0.75 | 3.0 | 6.0 | 96.0 | 24.0 |
| hpf | 4.0 | 0.38 | 0.094 | 0.5 | 0.75 | 2.0 | 3.0 | 48.0 | 24.0 |
| PA2798 | 3.0 | 0.5 | 0.064 | 1.0 | 0.75 | 2.0 | 1.5 | 48.0 | 16.0 |
| hflK | 6.0 | 1.5 | 0.125 | 0.75 | 0.75 | 1.0 | 4.0 | 96.0 | 24.0 |
| glnD | 0.75 | 0.25 | 0.064 | 0.75 | 0.75 | 1.5 | 4.0 | 64.0 | 24.0 |
a
TGC, tigecycline; TET, tetracycline; CIP, ciprofloxacin; CAZ, ceftazidime; IPM, imipenem; ATM, aztreonam; FOF, fosfomycin; ERY, erythromycin; CHL, chloramphenicol.