TABLE 1.
MICs against WT and epa locus mutants of E. faecalis OG1RF
| Organism | E-test MIC (μg/ml)a |
||||
|---|---|---|---|---|---|
| CRO | AMP | DOR | MEM | DAP | |
| WT E. faecalis OG1RF | 24 | 0.5 | 6 | 4 | 1–2 |
| OG1RFepaA::aph(3′)-IIIa | >256 | 0.5 | >32 | 6 | 0.25–0.38 |
| OG1RFepaE::aph(3′)-IIIa | >256 | 1 | >32 | 12 | NT |
| OG1RFepaL::aph(3′)-IIIa | >256 | 1 | >32 | 12 | NT |
| OG1RFepaN::aph(3′)-IIIa | >256 | 1 | >32 | 24 | NT |
| OG1RFepaB::aph(3′)-IIIa | >256 | 1.5 | >32 | >32 | 1.5–2 |
| OG1RFΔepaB | >256 | 2 | >32 | >32 | 1–2 |
| OG1RFΔepaB::epaB | 24 | 1 | 4 | 4 | 1–2 |
a
CRO, ceftriaxone; AMP, ampicillin; DOR, doripenem; MEM, meropenem; DAP, daptomycin; NT, not tested.