TABLE 2.

IC₅₀s of zidebactam, WCK 5153, and reference drugs cefepime and amdinocillin for PBPs of reference strain K. pneumoniae 52145

K. pneumoniae 52145 PBPa	Mean IC50 ± SD (μg/ml)b
	Cefepime	Amdinocillin	Zidebactam	WCK 5153
1a	1.2 ± 0.47	>2	>2	>2
1b	>2	>2	>2	>2
2	0.74 ± 0.27	0.18 ± 0.07	0.08 ± 0.02	0.07 ± 0.03
3	0.19 ± 0.08	>2	>2	>2
4	>2	>2	>2	>2
5/6	>2	>2	>2	>2

^aPBP, penicillin binding protein.

^bMean values ± standard deviations from at least 3 independent experiments are shown.