TABLE 2.
Susceptibility by ICU status, source of P. aeruginosa isolate, infection onset, and hospital characteristicsa
| Characteristic | No. of isolates | % susceptibility |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ESC |
Carb |
TZP |
AG |
FQ |
||||||||||
| Single agent | FQ combo | AG combo | Single agent | FQ combo | AG combo | Single agent | FQ combo | AG combo | Single agent | FQ combo | Single agent | AG combo | ||
| All | 11,701 | 79.0 | 86.1 | 90.0 | 79.3 | 85.0 | 90.2 | 85.0 | 90.5 | 93.3 | 82.5 | 87.7 | 72.7 | 87.7 |
| ICU status | ||||||||||||||
| ICU | 5,157 | 77.9 | 85.3 | 90.7 | 76.7 | 83.1 | 90.1 | 83.7 | 89.8 | 93.4 | 84.2 | 88.0 | 72.2 | 88.0 |
| Non-ICU | 6,544 | 79.8 | 86.7 | 89.5 | 81.4 | 86.5 | 90.3 | 86.0 | 91.1 | 93.1 | 81.1 | 87.5 | 73.1 | 87.5 |
| Source | ||||||||||||||
| Respiratory | 10,465 | 77.9 | 85.3 | 89.3 | 78.3 | 84.2 | 89.6 | 84.2 | 89.9 | 92.8 | 81.5 | 87.0 | 71.7 | 87.0 |
| Blood | 1,236 | 87.9 | 93.0 | 95.9 | 87.8 | 91.7 | 95.7 | 91.5 | 95.5 | 97.4 | 90.7 | 93.6 | 81.5 | 93.6 |
| Onset | ||||||||||||||
| Hospital | 6,445 | 76.2 | 84.7 | 89.7 | 76.1 | 82.9 | 89.2 | 82.2 | 89.2 | 92.8 | 82.6 | 87.3 | 71.2 | 87.3 |
| Admission | 5,256 | 82.4 | 87.8 | 90.4 | 83.3 | 87.6 | 91.5 | 88.4 | 92.1 | 93.9 | 82.2 | 88.2 | 74.6 | 88.2 |
| Urban/rural | ||||||||||||||
| Urban | 11,176 | 78.6 | 85.8 | 89.8 | 79.2 | 84.9 | 90.1 | 84.6 | 90.2 | 93.1 | 82.3 | 87.5 | 72.5 | 87.5 |
| Rural | 525 | 86.7 | 93.1 | 94.5 | 82.1 | 88.0 | 93.9 | 91.6 | 95.8 | 97.1 | 86.1 | 91.4 | 77.0 | 91.4 |
| Teaching status | ||||||||||||||
| Nonteaching | 6,904 | 77.5 | 84.8 | 89.1 | 77.4 | 83.7 | 89.0 | 83.6 | 89.6 | 92.5 | 81.2 | 86.9 | 71.2 | 86.9 |
| Teaching | 4,797 | 81.1 | 88.0 | 91.4 | 82.1 | 86.8 | 92.0 | 86.9 | 91.8 | 94.5 | 84.3 | 88.9 | 74.9 | 88.9 |
| Bed size | ||||||||||||||
| >300 | 8,216 | 76.9 | 84.8 | 88.9 | 77.4 | 83.8 | 89.1 | 83.3 | 89.4 | 92.4 | 81.5 | 86.9 | 72.1 | 86.9 |
| 100–300 | 3,092 | 83.9 | 88.9 | 92.8 | 83.8 | 87.7 | 92.9 | 88.9 | 92.8 | 95.3 | 84.7 | 89.3 | 73.8 | 89.3 |
| <100 | 393 | 83.0 | 90.3 | 92.4 | 85.0 | 89.6 | 93.9 | 89.1 | 94.4 | 95.7 | 85.8 | 92.1 | 78.6 | 92.1 |
| CDC region | ||||||||||||||
| South | 5,785 | 80.0 | 87.2 | 90.6 | 80.3 | 86.0 | 90.5 | 86.2 | 91.6 | 93.9 | 82.8 | 88.3 | 74.6 | 88.3 |
| Midwest | 3,293 | 77.7 | 85.3 | 88.9 | 77.8 | 83.8 | 89.3 | 83.8 | 89.7 | 92.3 | 80.4 | 86.4 | 71.1 | 86.4 |
| West | 1,428 | 77.7 | 83.4 | 90.5 | 78.9 | 82.9 | 90.7 | 80.8 | 86.5 | 92.7 | 84.9 | 88.4 | 70.6 | 88.4 |
| Northeast | 1,195 | 78.9 | 86.2 | 89.7 | 79.2 | 86.0 | 90.8 | 87.1 | 92.2 | 93.6 | 83.0 | 87.7 | 71.0 | 87.7 |
a
AG, aminoglycoside (gentamicin, tobramycin, amikacin); Carb, carbapenem (imipenem, meropenem); CDC, Centers for Disease Control and Prevention; combo, combination antibiogram; ESC, extended-spectrum cephalosporins (ceftazidime, cefepime); FQ, fluoroquinolone (ciprofloxacin, levofloxacin); ICU, intensive care unit; TZP, piperacillin-tazobactam.