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. 2002 Jul 31;35(4):221–235. doi: 10.1046/j.1365-2184.2002.00241.x

Figure 8.

Figure 8

Kinetics of LOOH‐induced changes in cellular GSH, GSSG and GSH‐to‐GSSG ratio in CaCo2 cells. CaCo‐2 cells grown in serum‐free DMEM were treated with 1 or 5 µM LOOH for 0–24 h. At designated times, cells were harvested and processed for HPLC analysis of cellular GSH/GSSG status. Panels (a), (b) and (c) represent GSH, GSSG and GSH‐to‐GSSG ratio in cells treated with 1 µM LOOH, respectively. Panels (d), (e) and (f) represent GSH, GSSG and GSH‐to‐GSSG ratio in cells treated with 5 µM LOOH, respectively. Each value is the mean ± SE of four separate experiments. * P  < 0.05 versus 0 min control; ** P  < 0.05 versus 30 min.