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. 2001 Dec 18;98(26):14937–14942. doi: 10.1073/pnas.251265598

Figure 3.

Figure 3

Free energy difference between each residue's contribution to the binding with drugs and substrate (ΔΔGres = ΔGInline graphic–ΔGInline graphic). All residue numbers are labeled for Saquinavir, but only a few residues are labeled for other drugs. Solid black line = dimer; red and blue lines = monomer.