Table 1.
Comparison of characteristics of rabbit BM‐MSC in normal and immortality phases
| Phase | Passage number | Differentiation potential | CFU‐F assay (%) | Aneuploidy | Soft agar colony formation | Tumour formation in NOD/SCID mice | ||
|---|---|---|---|---|---|---|---|---|
| Osteocyte | Chondrocyte | Adipocyte | ||||||
| Normal | Pn 1 | 10/10 | 10/10 | 10/10 | 40 ± 10 | 0/10 | 0/10 | 0/10 |
| Immortal | Pi 1 | 7/7 | 0/7 | 0/7 | 58 ± 2 | 0/7 | 0/7 | 0/7 |
| Pi 10 | 7/7 | nd | nd | 57 ± 3 | 0/7 | 0/7 | nd | |
| Pi 30 | 7/7 | nd | nd | 59 ± 3 | 1/7 | 0/7 | 0/7 | |
| Pi 50 | 7/7 | nd | nd | 60 ± 3 | 5/7 | 0/7 | nd | |
| Pi 80 | 7/7 | 0/7 | 0/7 | 63 ± 4 | 7/7 | 0/7 | 0/7 | |
nd, not determined; CFU‐F, colony‐forming unit‐fibroblast.