Figure 7.

Measurement of CDK1 activity – histone H1 kinase assay. Activity of CDK1 was analysed in GV oocytes (GV), in maturing oocytes 6 h after GVBD (control) and in oocytes treated with different concentrations of curcumin (10, 30, 50 μm). (A) Mean % of CDK1 activity from three experiments after densitometric analysis. (B) Representative image from one of three independent experiments. 10 μm curcumin increased CDK1 activity and 30 and 50 μm curcumin decreased CDK1 activity.