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Figure 5.

Figure 5

Serum‐dependent effects of the cytokines on HUVEC (▪) and MIEC (▒) expressed as percentage increase over untreated controls. Three thousand cells/well were incubated for 24 h in serum‐free basal medium (a) or in medium with FCS (b), in the presence or absence (control) of 100 ng/ml of the respective growth factor. The proliferative response of MIEC to growth factors is more dependent on serum presence than that of HUVEC. Note that at this seeding density PlGF‐1 and PlGF‐2 elicited a mitogenic effect also in HUVEC *P < 0.05, #P < 0.01, §P < 0.001 vs. untreated control.