Figure 6.

Circ_0078767 increased RASSF1A expression by inhibiting miR‐330‐3p. A, Circ_0078767 was increased by the transfection of the circ_0078767 vector in both non‐small‐cell lung cancer (NSCLC) cell lines. B, NSCLC cell lines were transfected with circ_0078767, and the subsequent downregulation of miR‐330‐3p expression was detected via qRT‐PCR. C, qRT‐PCR results showed that RASSF1A was upregulated by circ_0078767. D, Western blot results showed that RASSF1A was upregulated by circ_0078767. E, RIP experiments were performed using the anti‐RASSF1A antibody to immunoprecipitate RNA and a primer to detect miR‐330‐3p. Significantly decreased enrichment of miR‐330‐3p was identified in cells transfected with the circ_0078767‐overexpressing vector. The data are from one representative experiment among three that were performed identically and are expressed as the means ± SD. **P < 0.01