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. 2018 Dec 3;52(2):e12548. doi: 10.1111/cpr.12548

Figure 7.

Figure 7

Circ_0078767 regulates cell proliferation and cell cycle via the miR‐330‐3p/RASSF1A pathway. A, The structures of si‐circRNA and si‐NC vector are shown. B, Circ_0078767 was silenced by the transfection of specific silencing vectors in both cervical cell lines. C, CCK‐8 assay showed that inhibiting circ_0078767 expression promoted the cell proliferation rate of both cell lines; however, co‐transfection of an miR‐330‐3p inhibitor or RASSF1A significantly reversed this effect. D, FACS flow cytometry assay suggested that the alleviated G0/G1 phase arrest of both cell lines induced by si‐circ_0078767 was significantly abrogated by co‐transfection with an miR‐330‐3p inhibitor or RASSF1A. The data are from one representative experiment among three that were performed identically and are expressed as the means ± SD. **< 0.01