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Coronopilin‐induced mitotic block in U937 cells is followed by caspase‐independent apoptotic death. (a) U937 cells incubated with vehicle only or 20 μm coronopilin ± Z‐VAD (20 μm) for 48 h. For details and abbreviations, see legend to Fig. 3b; results are means ± SD of at least three experiments performed in duplicate (*P < 0.05 versus samples without Z‐VAD). (b) Western blot analysis of caspase‐3 cleavage in U937 cells treated with 20 μm coronopilin (CP) ± Z‐VAD for indicated times.
