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Table 3.

The effect of 10 µm 5′‐AdTdR on the TK1 activity of non‐irradiated cells in vitro at different concentrations of dTdR in the culture medium. TK1 activity was measured at substrate concentrations of 5 and 60 µm dTdR. Mean values ± SE of three experiments are given

Conc. dTdR in assay (µm) TK activity (dpm/103 S + G2 cells/min) dTdR in medium (µM)
− 5′‐AdTdR + 5′‐AdTdR
0 30 60 30 60
 5 172 ± 5 118 ± 2  64 ± 4 222 ± 2 174 ± 5
60 349 ± 6 166 ± 7 155 ± 10 383 ± 2 357 ± 10