Figure 3.

Porphyromonas gingivalis lipopolysaccharides ( Pg‐ LPS) at 0.1 μg/ml promoted and Pg‐ LPS at 10 μg/ml inhibited capacity of bone marrow mesenchymal stem cells ( BMMSC s) to inhibit activated T cells. BMMSCs pre‐treated with different concentrations (0, 0.1, 1 and 10 μg/ml) of Pg‐LPS for 12 h, were co‐cultured with activated splenocytes (SP) cells at 1:1 ratio for 48 h; then apoptosis of T cells was assessed by percentage annexin V‐positive cells. Results are representative of three independent experiments expressed as mean ± SD, n = 4; statistical significance is shown as (*) P < 0.05, compared to BMMSCs without Pg‐LPS treatment. LPS, lipopolysaccharides from Porphyromonas gingivalis.