Table 2.
The proliferative response of T and B cells to the different MSC sources. Table shows the results of: three BM MSCs in HS, three in LP and six in FBS; six CV in HS, three CV in LP and five CV in FBS; three AF in HS and eight in FBS. (IP) inhibition percentage of lymphocyte proliferation
| CV MSCs HS | CV MSCs PL | CV MSCs FBS | AF MSCs HS | AF MSCs FBS | BM MSCs HS | BM MSCs PL | BM MSCs FBS | |
|---|---|---|---|---|---|---|---|---|
| Direct contact | IP | IP | IP | IP | IP | IP | IP | IP |
| PB‐MNC | 24% | 35% | 74% | 20% | 23% | 47% | 20% | 24% |
| CD4+ cells | 31% | 53% | 65% | 34% | 35% | 57% | 24% | 31% |
| CD8+ cells | – | – | – | 47% | 39% | – | 41% | 52% |
| CD19+ cells | 31% | – | – | – | ‐ | – | – | – |
| Transwell | IP | IP | IP | IP | IP | IP | IP | IP |
| PB‐MNC | 16% | 16% | 58% | 33% | 46% | 28% | 20% | 30% |
| CD4+ cells | – | – | 68% | – | 40% | – | 28% | – |
| CD8+ cells | 64% | – | 35% | – | 44% | 36% | – | 33% |
| CD19+ cells | 40% | – | – | – | – | 30% | – | – |
AF, amniotic fluid; BM, bone marrow; CV, chorionic villi; HS, human allogeneic serum; MSCs, mesenchymal stem cells; PL, platelet lysate.