Table 3.
Genes downregulated in hMSC culture (fold change > 5)
| Gene Symbol | Description | Fold change‐P5 | Fold change‐P8 | |
|---|---|---|---|---|
| 1 | NRN1 | Neuritin 1 | — | 7.67 down |
| 2 | IFNA21 | Interferon, alpha 21 | — | 7.23 down |
| 3 | KRTAP13‐3 | Keratin‐associated protein 13‐3 | — | 6.64 down |
| 4 | HIST1H4L | Histone cluster 1, H4l | — | 6.58 down |
| 5 | TRHDE | Thyrotropin‐releasing hormone degrading enzyme | — | 6.32 down |
| 6 | MT1IP | Metallothionein 1I (pseudogene) | — | 6.23 down |
| 7 | PTGER2 | Prostaglandin E receptor 2 (subtype EP2), 53 kDa | — | 6.13 down |
| 8 | PCDH11Y | Protocadherin 11 Y‐linked | 6.55 down | 6.05 down |
| 9 | HEPH | Hephaestin | — | 5.99 down |
| 10 | OSTBETA | Organic solute transporter beta | — | 5.90 down |
| 11 | FBLN1 | Fibulin 1 | — | 5.83 down |
| 12 | OSTbeta | Organic solute transporter beta | — | 5.69 down |
| 13 | LCE2D | Late cornified envelope 2D | — | 5.36 down |
| 14 | HGF | Hepatocyte growth factor | — | 5.11 down |
| 15 | DPPA3 | Developmental pluripotency associated 3 | — | 5.07 down |
| 16 | OR5M3 | Olfactory receptor, family 5, subfamily M, member 3 | — | 5.03 down |
| 17 | EIF2S2 | Eukaryotic translation initiation factor 2, subunit 2 bet | 7.36 down | — |
| 18 | IFNA17 | Interferon, alpha 17 | 6.44 down | — |
| 19 | MS4A4A | Membrane‐spanning 4‐domains, subfamily A | 6.33 down | — |
The fold change is related to passage 1.
(—) Not differentially expressed.