Table 1.
Previously reported biomarkers of CD8+Tregs
| CD8+Tregs | Gene symbol | Regulation | Fold change | P‐value | Reference |
|---|---|---|---|---|---|
| CD8+ CD122+ | CD122/IL2RB | Up | 1.38 | 0.045* | 12 |
| CD8+ CD103+ | CD103 | Up | 1.12 | 0.33 | 13 |
| CD8+LAG‐3+Foxp3+ CTLA‐4+ | CD152/CTLA‐4 | Up | 1.97 | 0.021* | 14 |
| CD8+ CD28− | CD28 | Down | −1.59 | 0.028* | 15 |
| CD8+ CD75s+ | CD75s/ST3GAL1 | Up | 1.05 | 0.024* | 16 |
| CD8+ IL‐16+ | IL‐16 | Up | 1.61 | 0.0067* | 17 |
| CD8+ IL‐10+ | IL‐10 | Up | 1.23 | 0.067 | 18 |
| CD8+ CD28− CD56+ | CD56/NCAM1 | Up | 1.49 | 0.011* | 19 |
| CD8+ CD25+ Foxp3+ LAG3+ | LAG3 | Up | 1.95 | 0.018* | 20 |
| CD8+ CD11c+ | CD11c/ ITGAX | Up | 6.03 | 0.0023* | 21 |
| CD8+ CD44−CD103+ | CD44 | Down | 1.14 | 0.13 | 22 |