Table 1.
Proliferation of liver from non‐transplanted and transplanted animals throughout the study (mean ± SE)
| Time | PCNA labelling index | PCNA labelling index | ||||||
|---|---|---|---|---|---|---|---|---|
| 24 h | 7 d | 30 d | 90 d | 24 h | 7 d | 30 d | 90 d | |
| C | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 |
| C + RS | 0.9 ± 0.1 | 0.8 ± 0.2 | 0.9 ± 0.3 | 0.7 ± 0.2 | 0.9 ± 0.1 | 0.8 ± 0.2 | 0.9 ± 0.3 | 0.7 ± 0.2 |
| C + T3 | 2.8 ± 0.4 | 2.3 ± 0.2 | 2.9 ± 0.3 | 2.9 ± 0.2 | 2.8 ± 0.4 | 2.3 ± 0.2 | 2.9 ± 0.3 | 2.9 ± 0.2 |
| Time | Foetal hepatocytes | Adult hepatocytes | ||||||
| 24 h | 7 d | 30 d | 90 d | 24 h | 7 d | 30 d | 90 d | |
| Tx | 3.4 ± 0.2 | 3.4 ± 0.1 | 3.5 ± 0.3 | 2.8 ± 0.5 | 2.7 ± 0.2 | 2.8 ± 0.7 | 3.0 ± 0.8 | 3.2 ± 0.7 |
| Tx + RS | 3.5 ± 0.5 | 3.6 ± 0.2 | 3.6 ± 0.4 | 2.7 ± 0.2 | 3.0 ± 0.4 | 3.2 ± 0.9 | 3.1 ± 0.2 | 3.3 ± 0.7 |
| Tx + T3 | 4.1 ± 0.3 | 4.5 ± 0.4 | 4.7 ± 0.6 | 4.7 ± 0.3 | 4.0 ± 0.4 | 4.3 ± 0.7 | 4.43 ± 0.3 | 4.5 ± 1.0 |
| Tx + RS + T3 | 4.0 ± 0.2 | 4.5 ± 0.2 | 4.6 ± 0.3 | 4.8 ± 0.3 | 4.3 ± 0.5 | 4.3 ± 0.3 | 4.6 ± 0.2 | 4.7 ± 0.3 |
The upper part of the table shows LI from non‐transplanted Gunn rats: C (non‐treated rats, n = 6), C + RS (RS‐pre‐treated rats, n = 6), C + T3 (T3‐stimulated rats, n = 6). The lower part of the table shows the LI from Gunn rats transplanted with fetal (left) and adult (right) hepatocytes: Tx (non‐treated rats), Tx + RS (RS‐pre‐treated rats, n = 6), Tx + T3 (T3‐stimulated rats, n = 6) and Tx + RS + T3 (treated with RS and T3, n = 6).