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Table 1.

Cyclin‐CDK complexes are activated at specific points of the cell cycle. CAK, CDK activating kinase

CDK Cyclin Cell cycle phase activity
CDK4 Cyclin D1, D2, D3 G1 phase
CDK6 Cyclin D1, D2, D3 G1 phase
CDK2 Cyclin E G1/S phase transition
CDK2 Cyclin A S phase
CDK1 (cdc2) Cyclin A G2/M phase transition
CDK1 (cdc2) Cyclin B Mitosis
CDK7 Cyclin H CAK, all cell cycle phases