Skip to main content
. 2001 Dec 18;98(26):14973–14978. doi: 10.1073/pnas.261574498

Figure 1.

Figure 1

Reduction of cytosolic β-catenin levels and LEF-1 reporter activity in response to β-catenin antisense ODN transfection. (A) SW620 cell lysate was analyzed for cytosolic β-catenin levels by Western blotting 48 h posttransfection with β-catenin antisense and RC ODN in duplicated experiments. AS, antisense; RC, reverse control. (B) SW620 cells were transfected with β-catenin AS and RC ODN. After 24 h, the cells were transfected with reporter constructs as described in Methods. LEF-1 reporter activity was determined an additional 24 h later.