Figure 4.

Natural compounds utilized in ovarian cancer. In ovarian cancer cells, Withaferin A can inhibit population growth and colony formation of CaOV3 and SKOV3 cells by inducing apoptosis and cell cycle arrest through down‐regulation of Notch1, Notch3, Cdc25C, total and phosphorylation of Akt, and Bcl‐2 proteins. Honokiol has many effects on ovarian tumours, such as being antioxidant, anti‐thrombotic, anti‐inflammatory, xanthine oxidase inhibitory, having an anxiolytic effect, which can significantly suppress cell proliferation.