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. 2012 Jul 6;45(5):466–476. doi: 10.1111/j.1365-2184.2012.00833.x

Figure 2.

Figure 2

Core autophagic signalling pathways in cancer cells. Autophagy may decide the ultimate fate of cancer cells for regulation of key survival or death signalling pathways, such as Beclin‐1 complex, PI3K/Akt/mTOR, Ras/Raf/MAPK, BCR‐ABL, p53 and FOXO1 signalling in many types of cancer cells.