Table 2.
Effects of administration of HgCl2 on renal tubular injury score and serum urea nitrogen of female irradiated mice transplanted with female GFP+ HLMCs together with male GFP− cloned cultured MSCs
| Parameter | n | Pre‐HgCl2 | Post‐HgCl2 | ||
|---|---|---|---|---|---|
| Day 3 | Day 7 | Day 14 | |||
| Tubular injury score | |||||
| Group CON | 5 | 0.13 ± 0.02 | 0.11 ± 0.01 | 0.12 ± 0.02 | 0.13 ± 0.02 |
| Group HgCl2 | 5 | 0.12 ± 0.02 | 3.45 ± 0.03 [Link] , [Link] | 1.16 ± 0.03 [Link] , [Link] | 0.12 ± 0.01 |
| Serum urea nitrogen (mg/dL) | |||||
| Group CON | 5 | 19.6 ± 1.7 | 18.2 ± 2.1 | 17.8 ± 3.1 | 18.7 ± 2.8 |
| Group HgCl2 | 5 | 20.4 ± 2.6 | 63.1 ± 3.2 [Link] , [Link] | 38.2 ± 2.4 [Link] , [Link] | 20.2 ± 2.5 |
Values are mean ± SEM. GFP, green fluorescent protein; HLMCs, haematopoietic lineage marrow cells; MSCs, mesenchymal stem cells; significant at a P < 0.05 versus the same group at pre‐HgCl2 period; b P < 0.05 versus group CON at the corresponding time point.