Table 2.
Group differences in T cell repertoire for PI and NA youth.
| Cell Type | PI1 (n = 45) % | Control1 (n = 39) % | Adj. group difference* | 95% CI | P | Corrected P | Cohen’s F2 |
|---|---|---|---|---|---|---|---|
| CD4+ | 54.7 (8.6) | 59.9 (7.2) | −0.101 | −0.175 to −0.028 | 0.007 | 0.021 | 0.01 |
| CD4+ CD57+ | 2.6 (1.9) | 1.8 (1.7) | 0.060 | 0.013–0.106 | 0.012 | 0.030 | 0.08 |
| CD4+ CD57+ Naïve | 0.5 (0.4) | 0.5 (0.8) | 0.006 | −0.022 to 0.035 | 0.648 | 0.648 | 0.003 |
| CD4+ CD57+ CM | 2.3 (1.3) | 2.1 (1.8) | 0.015 | −0.026 to 0.056 | 0.463 | 0.579 | 0.007 |
| CD4+ CD57+ EM | 8.1 (5.0) | 5.2 (3.6) | 0.116 | 0.039–0.193 | 0.004 | 0.02 | 0.11 |
| CD4+ CD57+ TEMRA | 10.0 (11.8) | 8.4 (10.5) | 0.064 | −0.079 to 0.209 | 0.374 | 0.579 | 0.01 |
| CD8+ | 36.0 (7.4) | 32.3 (7.3) | 0.074 | 0.004–0.144 | 0.040 | 0.040 | 0.06 |
| CD8+ CD57+ | 21.4 (11.4) | 16.1 (10.7) | 0.139 | 0.013–0.265 | 0.032 | 0.040 | 0.06 |
| CD8+ CD57+ Naïve | 2.1 (2.3) | 3.7 (7.7) | −0.046 | −0.132–0.041 | 0.300 | 0.300 | 0.01 |
| CD8+ CD57+ CM | 18.9 (12.3) | 12.5 (11.1) | 0.234 | 0.080–0.389 | 0.003 | 0.005 | 0.12 |
| CD8+ CD57+ EM | 41.6 (17.1) | 28.0 (20.2) | 0.359 | 0.169–0.548 | < 0.001 | 0.002 | 0.18 |
| CD8+ CD57+ TEMRA | 43.6 (20.5) | 29.3 (15.5) | 0.302 | 0.119–0.485 | 0.002 | 0.005 | 0.14 |
Numbers in bold indicate P < .05.
*
Group difference of arcsine transformation and adjusted for sex, time of blood draw, and age at blood draw, with PI=1 and Control=0. Cohen’s F2 as difference in effect sizes with group and without group as a predictor.
1
Mean and (SD).