Table 3.
Difference in mortality among patients who had completed 6 h-sepsis resuscitation bundle components and those not completed as per logistic regression analysis
| Resuscitation bundle | Number of patients (completed vs. not completed) | In hospital mortality |
Odds ratio (CI) | P | |
|---|---|---|---|---|---|
| Completed (%) | Not completed (%) | ||||
| 1. Serum lactate measurement | 147 versus 53 | 34.69 | 54.71 | 0.44 (0.23-0.83) | 0.01 |
| 2. Sending blood cultures before antibiotics | 40 versus 160 | 40 | 40 | 1.0 (0.49-2.02) | 1.00 |
| 3. Broad-spectrum antibiotics | 181 versus 19 | 40.88 | 31.57 | 1.5 (0.545-4.12) | 0.431 |
| 4. Fluids bolus administration | 15 versus 29 | 13.33 | 82.75 | 0.03 (0.005-0.19) | 0.0001 |
| 5. CVP >8 mm Hg | 9 versus 35 | 11.11 | 71.42 | 0.05 (0.06-0.45) | 0.001 |
| 6. Optimization of Scvo2 >70% | 3 versus 41 | 0 | 63.41 | - | 0.031 |
| 7. Composite bundle completed | 19 versus 181 | 15.79 | 42.54 | 0.25 (0.07-0.9) | 0.024 |
CVP: Central venous pressure, Scvo2: Central venous oxygen saturation