Table 2.

Recovery and matrix effect for neurounina-1 in eight different lots of beagle dog plasma (4 normal, 2 lipemic, and 2 hemolysate).

Neurounina-1 concentration	1.5 ng/mL			400 ng/mL
	Standard solution	Spiked blank plasma extract sample	Extracted sample	Standard solution	Spiked blank plasma extract sample	Extracted sample
Individual peak area values	123.5	133.8	125.0	32951	31780.1	29320.2
	107.3	131.9	106.9	32867.8	32355.4	31935.9
	145.2	126.5	120.7	33273.9	34053.7	29296.7
Mean	125.3	130.7	117.5	33031	32730	30184
CV(%)	15.2	2.9	8.0	0.6	3.6	5.0
Recovery(%)	89.9			92.2
Matrix effect(%)	93.8			91.4

CV %, coefficient of variation = [(SD/M) × 100]; M, mean; SD, standard deviation of M.