Table 3.
Stability tests for neurounina-1 in beagle dog plasma.
| Estability | Freeze/thaw (4cycles) |
Short-term (6 h) |
Post-processing (52 h) |
|||
|---|---|---|---|---|---|---|
| Concentration | (1.5 ng/mL) | (400 ng/mL) | (1.5 ng/mL) | (400 ng/mL) | (1.5 ng/mL) | (400 ng/mL) |
| Individual value | 1.44 | 401.76 | 1.37 | 419.00 | 1.39 | 398.17 |
| 1.39 | 403.30 | 1.34 | 426.97 | 1.62 | 407.43 | |
| 1.35 | 410.78 | 1.55 | 432.58 | 1.32 | 416.33 | |
| Mean | 1.39 | 405 | 1.42 | 426 | 1.44 | 407 |
| CV(%) | 3.2 | 1.2 | 8.0 | 1.6 | 10.9 | 2.2 |
| Accuracy(%) | 92.7 | 101.3 | 94.7 | 106.5 | 96.0 | 101.8 |
CV% = [(SD/M) × 100]; Accuracy % = [(E - T)/T] × 100; CV, coefficient of variation; M, mean; SD, standard deviation of M; E, experimentally determined concentration; T, theoretical concentration.