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. Author manuscript; available in PMC: 2019 May 2.
Published in final edited form as: ACS Synth Biol. 2018 Nov 29;7(12):2898–2907. doi: 10.1021/acssynbio.8b00368

Table 1.

Binding affinities of LANS for importin α7 in the dark and light as well as light to dark fold-changes.

Affinity (μM)
LANS Dark Light Fold-change
WT 30.4 ± 18.0 1.3 ± 0.6 23.7
RLR 132.5 ± 74.9 5.1 ± 1.7 25.7
RVH 19.3 ± 4.9 2.3 ± 1.2 8.5