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. 2019 Apr 17;11:301–307. doi: 10.2147/CEOR.S177207

Table 4.

Sensitivity analyses

Comparing methods for identifying omalizumab responders Most cost-effective alternative Threshold
Likelihood that omalizumab candidate will be identified as an omalizumab responder via a trial of omalizumab therapy: 0.468 FeNO measurement + omalizumab trial No threshold
Likelihood that omalizumab candidate will be identified as an omalizumab responder via a trial of omalizumab therapy: 0.633 No threshold
Likelihood that omalizumab candidate will have FeNO >19.5 ppb: 0.434 FeNO measurement + omalizumab trial No threshold
Likelihood that omalizumab candidate will have FeNO >19.5 ppb: 0.587 No threshold
Likelihood that patient predicted to be an omalizumab responder (FeNO >19.5 ppb) will be confirmed as an omalizumab responder following a trial of therapy: 0.850 FeNO measurement + omalizumab trial No threshold
Likelihood that patient predicted to be an omalizumab responder (FeNO >19.5 ppb) will be confirmed as an omalizumab responder following a trial of therapy: 1.000 No threshold

Abbreviation: FeNO, fractional exhaled nitric oxide.