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. 2019 Apr 23;11:3381–3393. doi: 10.2147/CMAR.S198419

Table 1.

Characteristics of the included studies in this meta-analysis

Reference Year Country Disease type Patients (n) Male/female Included years Age (years)* Prognostic index Detection method Cut-off value Survival type
(analysis type)
Follow-up Treatments Stage
Hwang et al10 2017 Korea BC 793 0/793 2000–2016 54.1±12.3 FAR ROC curve 7.1 OS (M) ≥5 years With-surgery I-II-III
Tan et al11 2017 China ESCC 1135 888/247 2008–2010 58 (28–88) FAR X-tile software 0.08 OS (M) ≥5 years With-surgery NA
Zhang et al12 2017 China GC 360 261/99 2011–2013 58.24±11.22 AFR X-tile software 8.9 OS (M) <5 years With-surgery II -III
Xu et al16 2018 China HCC 151 128/23 2006–2010 51 (22–78) FAR ROC curve 0.062 OS (M) ≥5 years With-surgery BCLC (0-A-B-C)
Chen et al17 2018 China NSCLC 529 312/217 2010–2015 62 (28–82) AFR ROC curve 9.67 OS (M), DFS (M) ≥5 years With-surgery I-II-III
Li et al18 2018 China NSCLC 412 317/95 2005–2014 60.33±8.97 AFR X-tile software 7.8 OS (M) <5 years Mixed I-II-III-IV
Sun et al13 2018 China CRC 680 426/254 2008–2013 NA AFR X-tile software 9.2 OS (M) <5 years With-surgery I-II-III
Xu et al19 2018 China GBC 154 63/91 2005–2017 64 (29–85) FAR ROC curve 0.08 OS (M) ≥5 years With-surgery I-II-III-IV
Zou et al20 2018 China CLL 191 128/63 1995–2017 61 (23–86) AFR X-tile software 9.7 OS (M) ≥5 years Untreated Binet A-B-C stage
Liang et al21 2018 China STS 310 174/136 1999–2013 39 (5–78) FAR ROC curve 0.0726 OS (M), DFS (U) ≥5 years With-surgery I-II-III-IV
Gao et al22 2018 China ESCC 153 128/25 2011–2013 61.93±6.72 AFR X-tile software 9.3 OS (M) <5 years With-surgery 0-I-II-III
Du et al 23 2018 China GBC 220 122/98 2009–2015 NA AFR X-tile software 15.45 OS (M) <5 years Mixed Metastatic

Note: *Data shown as median (interquartile range) or mean ± standard deviation.

Abbreviations: BC, breast cancer; ESCC, esophageal squamous cell carcinoma; GC, gastric cancer; HCC, hepatocellular carcinoma; NSCLC, non-small cell lung cancer; CRC, colorectal cancer; GBC, gallbladder cancer; CLL, chronic lymphocytic leukemia; STS, soft tissue sarcoma; OS, overall survival; DFS, disease-free survival; AFR, albumin/fibrinogen ratio; FAR, fibrinogen/albumin ratio; ROC, receiver operating characteristic; M, multivariate analysis, U, univariate analysis, NA, not available.