Table 2.

Subgroup analysis for OS in the patient with malignant tumors

Stratified analysis	Studies (n)	Pooled results				Heterogeneity
HR	95% CI		P-value	I2 (%)	P
Tumor type
GI cancer	7	1.40		1.17–1.62	<0.001	37.6	0.142
Non-GI cancer	5	1.96		1.49–2.42	<0.001	0.0	0.780
Detection method
ROC curve	5	2.13		1.64–2.63	<0.001	0.0	0.791
X-tile software	7	1.38		1.16–1.60	<0.001	11.4	0.342
Follow-up time
<5 years	5	1.42		1.09–1.74	<0.001	18.4	0.297
≥5 years	7	1.56		1.30–1.81	<0.001	43.1	0.103
Treatment situation
With-surgery	9	1.54		1.31–1.76	<0.001	20.3	0.262
Mixed	2	1.30		0.84–1.77	NS	71.7	0.060
Untreated	1	3.47		1.54–7.82	<0.001	–	–

Abbreviations: OS, overall survival; HR, hazard ratio; CI, confidence interval; GI, gastrointestinal; ROC, receiver operating characteristic, NS, not significant.