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. 2018 Dec 12;20(5):925–933. doi: 10.1093/pm/pny241

Table 2.

Medication use pre- and post-TPIG

Medication No. of Participants (%)
Pre Post
Paracetamol (any form/combination) 92 (51.7) 88 (49.4)
Paracetamol sustained release dose >500 mg 32 (18.0) 41 (23.0)
Paracetamol >1 product 14 (7.9) 1 (0.6)
Nonsteroidal anti-inflammatory drug 62 (34.8) 77 (43.3)
Oral/suppository* 43 (24.2) 58 (32.6)
Topical 0 (0.0) 36 (20.2)
Ibuprofen + codeine combination 24 (13.5) 0 (0.0)
Opioids 123 (69.1) 134 (75.3)
Buprenorphine 9 (5.1) 38 (21.3)
Codeine and codeine-containing formulations 79 (44.4) 2 (1.1)
Fentanyl 4 (2.2) 0 (0.0)
Morphine 10 (5.6) 22 (12.4)
Oxycodone and oxycodone-containing formulations 48 (27.0) 7 (3.9)
Tramadol 8 (4.5) 29 (16.3)
Tapentadol 0 (0.0) 50 (28.1)
Other–dextropropoxyphene, hydromorphone, methadone 5 (2.8) 3 (1.7)
Benzodiazepines 49 (27.5) 15 (8.4)
Short acting (alprazolam, temazepam) 14 (7.9) 0 (0.0)
Long acting (clonazepam, diazepam, flunitrazepam) 38 (21.3) 15 (8.4)
Zolpidem/zopiclone 4 (2.2) 2 (1.1)
Adjuvants
Muscle relaxants (only baclofen, orphenadrine, or orphenadrine combinations) 3 (1.7) 67 (37.6)
Gabapentin/pregabalin 32 (18.0) 75 (42.1)
Selective serotonin reuptake inhibitors 14 (7.9) 3 (1.7)
Serotonin and noradrenaline reuptake inhibitors 12 (6.7) 47 (26.4)
Tricyclic antidepressants 29 (16.3) 61 (34.3)
None 26 (14.6) 2 (1.1)

TPIG = Turning Pain Into Gain program.

*

Excludes ibuprofen + codeine combinations.