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Apc-knockout mouse colon organoids (A, B, E, F) and human colorectal cancer (CRC) organoids (C, D, G, H) incubated in control nanoparticles (A, E, C, G) and functionalized nanoparticles (B, F, D, H) under brightfield microscopy and fluorescent microscopy. Scale bar is 100 μm. Mean fluorescent intensity (MFI) of (I) Apc-knockout mouse colon and (J) human CRC organoids incubated in control nanoparticles and folate-conjugated nanoparticles.
