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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Mater Today (Kidlington). 2018 Dec 23;23:16–25. doi: 10.1016/j.mattod.2018.11.001

Table 1.

Physical parameters of synthesized particles: size, the parameter characterizing poly-dispersity in size (PID), excitation/emission fluorescent maxima, fluorescent brightness, the zeta potential, and the number of folate molecules per single nanoparticle. For commercially available dyes were used to demonstrate the assembly of CA-dots fluorescent in the entire UV-VIS-NIR spectrum. Stilbene 420 (blue), Rhodamine 560 (green), Tracer Yellow (yellow), Methylene Blue (red/NIR) were used for encapsulation. Data for particles covered with PEG and PEG+folate are shown. Brightness relative to quantum dots was calculated for 1 QD450 41 (brightness 1 × 105 M−1 cm−1), 2 QD525 42 (brightness 1.3 × 105 M−1 cm−1), 3 QD585 42 (brightness 3.05 × 105 M−1 cm−1), QD705 43 (brightness 1.2 × 106 M−1 cm−1 ).

CA-dot Size, Mn (nm) PDI Ex/Em (nm/nm) Brightness (MBTU) / M cm−1 Brightness relative to QD (times) Zeta- Potential (mV) Folates per particle
CA-SB-PEG 61 0.22 400/445 89 ± 4 / (5.8±0.3) × 106 58 1 −8.0±1 N/A
CA-SB-PEG-FA 50 0.17 400/445 529 ± 42 / (3.4 ±0.3) ×107 340 1 −11±1 870±220
CAGREEN-PEG 77 0.13 495/525 870 ± 71 /(6.4 ±0.5) ×107 640 2 −17±2 N/A
CA- GREEN - PEG-FA 68 0.14 495/525 781 ± 49 / (5.8 ±0.4) × 107 580 2 −15±3 910±200
CA-YEL- PEG 60 0.15 450/560 159 ± 13 / (4.3±04) × 106 43 3 −3±2 N/A
CA- YEL - PEG-FA 87 0.11 450/560 649 ± 92 / (1.8 ±0.3) × 107 180 3 −7±1 1110±180
CA- RED/NIR- PEG 77 0.17 665/680 2554 ± 268 / (1.3 ±0.1) × 108 1300 4 −19±1 N/A
CA- RED/NIR - PEG-FA 63 0.20 665/680 318 ± 38 / (1.6 ±0.2) × 107 160 4 −12±2 930±290