Table 5:
Profiles of differentially expressed genes in β2AR-KO transgenic AD model annotated to be related to unfolded protein binding in Gene Ontology.
| Items | Gene ID | Fold Chg. | p Value | q Value |
|---|---|---|---|---|
| Eukaryotic translation initiation factor 2-alpha kinase 2 | 19106 | 2.220892 | 4.71E-07 | 0.00016 |
| DnaJ (Hsp40) homolog, subfamily C, member 16 | 214063 | 1.713747 | 1.49E-05 | 0.001453 |
| Cyclin D1 | 12443 | 1.489153 | 0.000724 | 0.016556 |
| DnaJ (Hsp40) homolog, subfamily C, member 18 | 76594 | 1.461304 | 0.000678 | 0.015844 |
| Wolfram syndrome 1 homolog (human) | 22393 | 1.289007 | 0.003984 | 0.045336 |
| SEC63-like (S. cerevisiae) | 140740 | 1.193609 | 0.001819 | 0.029331 |
| HERPUD family member 2 | 80517 | −1.22882 | 0.003121 | 0.039352 |
| Heat shock protein 90, alpha (cytosolic), Class A member 1 | 15519 | −1.23512 | 0.001109 | 0.021868 |
| Heat shock 105kDa/110kDa protein 1 | 15505 | −1.24793 | 0.001371 | 0.024635 |
| DnaJ (Hsp40) homolog, subfamily B, member 11 | 67838 | −1.29418 | 0.000546 | 0.014039 |
| Chaperonin containing Tcp1, subunit 3 (gamma) | 12462 | −1.35609 | 0.000138 | 0.006112 |
| Heat shock protein 90 alpha (cytosolic), class B | 15516 | −1.4133 | 0.000366 | 0.011053 |
| Heat shock protein 90, beta (Grp94), member 1 | 22027 | −1.41384 | 0.002119 | 0.031692 |
| T-complex protein 1 | 21454 | −1.41447 | 0.002478 | 0.034708 |
| Heat shock protein 5 | 14828 | −1.43609 | 0.001112 | 0.021872 |
| DnaJ (Hsp40) homolog, subfamily A, member 4 | 58233 | −1.46868 | 5.87E-05 | 0.00359 |
| DnaJ (Hsp40) homolog, subfamily C, member 3 | 100037258 | −1.50583 | 0.000205 | 0.007744 |
| Serine/arginine-rich splicing factor 10 | 14105 | −1.54974 | 0.002451 | 0.034597 |
| Heat shock protein 1 (chaperonin) | 15510 | −1.76402 | 0.000238 | 0.008435 |
| Heat shock protein 8 | 15481 | −1.8216 | 0.000412 | 0.011816 |
| Calreticulin | 12317 | −1.86027 | 0.001086 | 0.021609 |
| p53 and DNA damage regulated 1 | 68559 | −15.3898 | 1.55E-12 | 5.96E-09 |