Table 6:
Profiles of differentially expressed genes in β2AR-KO transgenic AD model annotated to be related to Alzheimer’s disease in KEGG’s pathways.
| Items | Gene ID | Fold Chg. | p Value | q Value |
|---|---|---|---|---|
| Cytochrome c oxidase, subunit VI a, polypeptide 2 | 12862 | 2.523729 | 1.44E-05 | 0.001417 |
| ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 11937 | 1.512032 | 0.000439 | 0.012244 |
| Beta-site APP-cleaving enzyme 2 | 56175 | 1.506286 | 8.44E-05 | 0.004494 |
| Inositol 1,4,5-triphosphate receptor 2 | 16439 | 1.451202 | 0.000228 | 0.008213 |
| Lipoprotein lipase | 16956 | 1.413552 | 0.000202 | 0.007714 |
| Apolipoprotein E | 11816 | 1.35843 | 0.000376 | 0.01129 |
| Caspase 8 | 12370 | 1.336963 | 0.003373 | 0.041103 |
| Calpain 1 | 12333 | 1.311871 | 0.001259 | 0.023432 |
| NADH dehydrogenase (ubiquinone) flavoprotein 3 | 78330 | 1.231451 | 0.004652 | 0.049888 |
| ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 | 11950 | −1.26575 | 0.004255 | 0.047107 |
| Guanine nucleotide binding protein, alpha q polypeptide | 14682 | −1.26842 | 0.003271 | 0.040466 |
| Phospholipase C, beta 4 | 18798 | −1.29642 | 0.000965 | 0.020124 |
| Anterior pharynx defective 1c homolog (C.elegans) | 68318 | −1.56577 | 0.000409 | 0.011797 |
| RIKEN cDNA 1500003O03 gene | 56398 | −1.58374 | 2.07E-05 | 0.001806 |
| Cytochrome c oxidase subunit VIIa polypeptide 2-like | 20463 | −10.3201 | 8.36E-14 | 1.12E-09 |