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. 2019 May 1;2019(5):CD004780. doi: 10.1002/14651858.CD004780.pub4

Summary of findings 3. Family therapy compared to educational interventions for anorexia nervosa.

Family therapy compared to educational interventions for anorexia nervosa
Participants: People of any age or gender with a primary clinical diagnosis of anorexia nervosa (AN)
Intervention: Family therapy
Comparator: Educational interventions
Outcomes № of participants
 (studies)
 Follow up Certainty of the evidence
 (GRADE) Relative effect
 (95% CI) Anticipated absolute effects* (95% CI)
Risk with educational interventions Risk difference with Family therapy
Remission at long‐term follow‐up ‐ other 30
 (1 RCT) ⊕⊝⊝⊝
 VERY LOWa,b,c RR 9.00
 (0.53 to 153.79) Study population
0 per 1000 0 fewer per 1000
 (0 fewer to 0 fewer)
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
 CI: Confidence interval; RR: Risk ratio;
GRADE Working Group grades of evidenceHigh certainty: We are very confident that the true effect lies close to that of the estimate of the effect
 Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
 Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect
 Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

aEvidence downgraded by one level for unclear risk of selection bias, due to inadequate reporting of random sequence generation and allocation concealment and also downgraded due to high risk of performance bias.
 bEvidence downgraded by one level for imprecision, as there was only one trial.
 cEvidence downgraded by one level for inconsistency, due to wide confidence intervals.