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. 2019 May 2;14(5):e0216173. doi: 10.1371/journal.pone.0216173

Table 1. Equation for calculating each grade including CTP score, MELD score, ALBI grade and PALBI grade.

CTP score Adding points of five categories below
CTP class Class A, 5–6 points Class B, 7–9 points Class C, 10–15 points
1 point 2 points 3 points
Albumin (g/dL) > 3.5 2.8–3.5 < 2.8
Bilirubin (mg/dL) < 2 2–3 >3
INR <1.7 1.7–2.3 >2.3
Ascites None Mild Severe
Encephalopathy None Grade I or II Grade III or IV
MELD score 3.78 x loge serum bilirubin (mg/dL) + 11.20 x loge INR + 9.57 x loge serum creatinine (mg/dL) + 6.43
MELD grade Grade 1, <10 Grade 2, 10–14 Grade 3, >14
ALBI score (log10 bilirubin × 0.66) + (albumin × -0.085), where bilirubin is in μmol/L and albumin in g/L
ALBI grade Grade 1, ≤-2.60 Grade 2,
>-2.60 to ≤-1.39
Grade 3, >-1.39
PALBI score 2.02 × log10 bilirubin − 0.37 × (log10 bilirubin)2 − 0.04 × albumin − 3.48 × log10 platelets + 1.01 × (log10 platelets) 2
PALBI grade Grade 1, ≤-2.53 Grade 2,
>-2.53 to ≤-2.09
Grade 3, >-2.09

CTP, Child-Turcotte-Pugh; INR, International normalized ratio; MELD, Model for end-stage liver disease; ALBI, albumin-bilirubin; PALBI, platelet-albumin-bilirubin