Table 2. Parameters and values used in the simulations.
When other values are used, they are specifically noted in the manuscript.
| Parameter | Value (unless otherwise noted) | Explanation |
|---|---|---|
| SA | 5 [1/MCS] | Secretion parameter for co-attractant (related to C3a) |
| SS | 20 [1/MCS] | Secretion parameter for NC attractant (related to Sdf1) |
| Sl | 0.7 [1/MCS] | Secretion parameter for inhibitor |
| DA | 8 [s.u.2/MCS] | Diffusion parameter for co-attractant |
| DS | 8 [s.u.2/MCS] | Diffusion parameter for NC attractant |
| DI | 0,005 [s.u.2 /MCS] | Diffusion parameter for inhibitor |
| δA | 0.006 [1/MCS] | Decay parameter for co-attractant |
| δS | 0.006 [1/MCS] | Decay parameter for NC attractant |
| δI | 0.0006 [1/MCS] | Decay parameter for inhibitor |
| λA | 1 | Attraction strength parameter for co-attractant |
| 150 = 150 * λS = 1 | Attraction strength parameter for NC attractant | |
| λI | -100 | Attraction strength parameter for inhibitor |
| λPNC | 6 | Self-propulsion strength parameter for NC |
| δPNC(free) | 0.3 | Self-propulsion polarity decay parameter for NC without contact |
| δPNC(contact) | 0.08 | Self-propulsion polarity decay parameter for NC with contact |
| λPPL | 12 | Self-propulsion strength parameter for placode |
| δPPL(free) | 0.5 | Self-propulsion polarity decay parameter for placode without contact |
| δPPL(contact) | 0.1 | Self-propulsion polarity decay parameter for placode with contact |
| λCIL | 0.5 | CIL repolarization parameter |
| λM | 5 | Persistent cell-cell adhesion strength parameter |
| λV | 5 | Cell incompressibility parameter |
| VT | 25 [s.u.2] | Cell volume |
| J(NC,0) | 5 | Surface-tension-like adhesion between NC and cell-free areas |
| J(NC,NC) | 3 | Surface-tension-like adhesion between NC |
| J(placode,0) | 5 | Surface-tension-like adhesion between placodes and cell-free areas |
| J(placode,NC) | 20 | Surface-tension-like adhesion between placodes and NC |
| J(placode,placode) | 10 | Surface-tension-like adhesion between placodes |