Table 1. Amino acid (aa) positions and sequences of the each four regions building the predicted protein-protein-interfaces patch I and patch II of ATP1B2 as well as corresponding aa sequences in ATP1B1.
ATP1B2 –putative interfaces | ATP1B1 | |||
---|---|---|---|---|
name | aa positions | aa sequence | corresponding aa sequence | |
Patch I | Region 1 | 158–163 | GNCSGI | GNCSGL |
Region 2 | 198–201 | VTCA | VQCT | |
Region 3 | 246–249 | VKFL | VQFT | |
Region 4 | 213–221 | NFVMFPANG | NVEYFGLGNSP | |
Patch II | Region 1 | 83–88 | MIRPKT | TQIPQI |
Region 2 | 108–121 | QKLNKFLEPYNDSI | LNIVRFLEKYKDSA | |
Region 3 | 181–184 | KMNR | KLNR | |
Region 4 | 240 | T | L |