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. 2019 Apr 22;15(4):e1006534. doi: 10.1371/journal.pcbi.1006534

Fig 2. Overview of the modeling and data fitting steps.

Fig 2

In Phase 1 we update our prior information on parameters (neff, μ) based on external data D0. In phase 2 we estimate all the parameters of the (mixture) model using MCMC, precomputed distance distributions pS and the information obtained in Phase 1. The fitted model can be used to e.g. obtain the same strain probability for a new (future) measurement.