Table 2.

Highly Probable Clinical Manifestations for Cardiac Sarcoidosis

1	Major criteria
(a)	High‐degree atrioventricular block (include complete atrioventricular block) or lethal ventricular arrhythmia (persistent ventricular tachycardia, ventricular fibrillation)
(b)	Basal septum thinning or anatomical abnormalities of ventricular wall (ventricular aneurysm, focal thinning, focal thickening)
(c)	Left ventricular systolic dysfunction (ejection fraction <50%) or focal ventricular wall motion abnormalities
(d)	Significant positive uptake in the heart on gallium citrate scintigraphy or 18F‐fluorodeoxyglucose positron emission tomography imaging
(e)	Late gadolinium enhancement on cardiac magnetic resonance imaging
2	Minor criteria
(f)	Ventricular arrhythmia in ECG (nonsustained ventricular tachycardia, multifocal or frequent premature ventricular contraction), bundle branch block, axis deviation, abnormal Q wave
(g)	Focal defect on single‐photon emission computed tomography
(h)	Monocyte infiltration and moderate‐severe fibrosis on endomyocardial biopsy

Consider as disease highly probable clinical manifestations if ≥2 of 5 major criteria (a–e) have been met. Consider as highly probable clinical manifestations if 1 of 5 major criteria (a–e) and 2 of 3 minor criteria (f–h) have been met.